Acute effects of intermittent hypoxia and acute aerobic exercise on Orexin-A level and blood pressure in pre-hypertensive patients

AUTHORS

Zeinab Abdi 1 , Vahid Tadibi 1 , * , Naser Behpoor 1

1 Department of Biological Sciences, Faculty of Physical Education and Sports Sciences, Razi University, Kermanshah, Iran

How to Cite: Abdi Z, Tadibi V , Behpoor N. Acute effects of intermittent hypoxia and acute aerobic exercise on Orexin-A level and blood pressure in pre-hypertensive patients, J Kermanshah Univ Med Sci. 2015 ; 19(3):e69872. doi: 10.22110/jkums.v19i3.2252.

ARTICLE INFORMATION

Journal of Kermanshah University of Medical Sciences: 19 (3); e69872
Published Online: July 19, 2015
Article Type: Original Article
Received: January 13, 2015
Accepted: June 30, 2015
Crossmark

Crossmark

CHEKING

READ FULL TEXT
Abstract

Background: This study was aimed to compare the effects of acute aerobic exercise and intermittent hypoxia on blood pressure and Orexin-A levels in patients with prehypertension.

Methods: To this end, 10 male and female volunteers with prehypertension (51.7±3.1 years old) performed an aerobic exercise and an intermittent hypoxia session in separate days. The aerobic exercise consisted of 40 minutes of running on treadmill with intensity of 70% heart rate reserve. During intermittent hypoxia session, 5 minutes hypoxic air (11% oxygen) and 5 minutes normoxic air (room air) were inhaled intermittently at sitting position for an hour. Orexin-A levels, systolic and diastolic blood pressure were measured before and after interventions.

Results: Systolic and diastolic blood pressure levels reduced significantly after aerobic exercise and intermittent hypoxia (P≤0.05). However Orexin-A levels decreased significantly only in intermittent hypoxic and this reduction was significantly correlated with the decrease in systolic blood pressure (P≤0.05).

Conclusion: Performing an aerobic exercise with moderate intensity as well as an intermittent hypoxic session can have beneficial effects on blood pressure in patients with prehypertension and can be advised for them. In addition, intermittent hypoxia can reduce Orexin-A levels in these people. Therefore, it can be proposed for those who cannot participate in aerobic exercise program.

Keywords

Orexin-A aerobic exercise hypocretin physical activity blood pressure hypoxia

© 2015, Journal of Kermanshah University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Fulltext

References

  • 1.

    The references of this article is available on PDF

  • COMMENTS

    LEAVE A COMMENT HERE: