Induction of growth and proliferation of fibroblast cells in magnetic field

AUTHORS

Naghmeh Ezatti 1 , Shiva Irani 1 , Seyed Mohammad Atyabi 2 , *

1 Dept. of Biology, School of Basic Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

2 Dept. of Pilot Biotechnology, Pasteur Institute of Iran, Tehran, Iran

How to Cite: Ezatti N , Irani S, Atyabi S M. Induction of growth and proliferation of fibroblast cells in magnetic field , J Kermanshah Univ Med Sci. 2015 ; 18(11):e73995. doi: 10.22110/jkums.v18i11.1874.

ARTICLE INFORMATION

Journal of Kermanshah University of Medical Sciences: 18 (11); e73995
Published Online: February 20, 2015
Article Type: Original Article
Received: August 11, 2014
Accepted: January 20, 2015
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Abstract

Background: Tissue engineering is generally defined as developing and changing the laboratory growth of molecules and cells in tissues or organs to replace and repair the damaged part of body. This study was carried out to stimulate the growth of cultured fibroblast cells by a physical electromagnetic method.

Methods: First, an air-core coil was prepared and the cell culture plate was placed comfortably into the mold, then the plate containing the culture medium and human fibroblast cell along with air-core coil were placed in an incubator and then connected to the power supply. Thus, the sample underwent electromagnetic field at different times, and cell proliferation was studied by MTTassay.

Results: Microscopic images indicated that the cells undergoing electromagnetic field (0.35 amps) had a significant growth compared to the cells in control group in a definit range of stimulation.

Conclusion: In conclusion, electromagnetic stimulation in a definite range led to cell proliferation and could be used as a positive factor in tissue engineering.

Keywords

Tissue engineering fibroblast cell electromagnetic stimulation

© 2015, Journal of Kermanshah University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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