Comparing dexamethasone and metoclopramide for preventing nausea and vomiting and pain after hernia inguinal surgery

AUTHORS

Rasool Kavyannejad 1 , * , MahmoodReza Kohan 2 , Zamane Hosaini 3 , Glaviz Zandkarimi 3

1 Intensive Care Unit (ICU), Imam Reza Hospital, Kermanshah University of Medical Science, Kermanshah, Iran

2 Dept. of Anesthesiology, School of Medicine, Kurdestan University of Medical Sciences, Sanandaj, Iran

3 School of Nursing, Kurdestan University of Medical Sciences, Sanandaj, Iran

How to Cite: Kavyannejad R, Kohan M, Hosaini Z, Zandkarimi G. Comparing dexamethasone and metoclopramide for preventing nausea and vomiting and pain after hernia inguinal surgery, J Kermanshah Univ Med Sci. 2013 ; 17(1):e77137.

ARTICLE INFORMATION

Journal of Kermanshah University of Medical Sciences: 17 (1); e77137
Published Online: April 29, 2013
Article Type: Research Article
Received: May 01, 2012
Accepted: September 25, 2012

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Abstract

Background: Postoperative nausea and vomiting (PONV) is the commonest consequence after surgery which can lead to multiple difficulties on different body systems. The aim of this study was to compare Dexamethasone and Metoclopramide effect in preventing PONV and pain.

Methods: In a clinical trial, 60 ASA 1-2 patients who were candidate for elective inguinal surgery were randomly divided into two equal groups. One group (M) received the intravenous 10mg Metoclopramide and the other group (D) received 8mg Dexamethasone 10 min before extubation and 6 hours after the end of the surgery. The indication of PONV, the time to the first request for analgesic and the amount of analgesic in the course was recorded 24 hours after surgery. Data was analyzed using SPSS version 16.

Results: The indication of PONV had no significant difference in both groups (P>0.05). The time to the first request for analgesic in group (M) was less than group (D) (p=0.063) and the amount of used analgesic in group (D) was less than group (M) (p=0.177) but had no significant difference. Prescription frequency of analgesic was significantly lower in dexamethasone group (P=0.033). 

Conclusion: There was no statistically significant difference between two groups in the rate of PONV, but due to the analgesia effects of Dexamethasone, using this drug after surgery is recommended.

Keywords

metoclopramide dexamethasone postoperative nausea and vomiting pain

© 2013, Journal of Kermanshah University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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