Intravenous lidocaine on intraocular pressure in cataract surgery patients under sedation

AUTHORS

Mitra Yari 1 , * , Parisa Golfam 2 , Hamid Ariaietabar 3 , Fariba Sheikhi 3 , Nasser Yegane 2 , Mansour Rezaei 4 , Diako Sobhi 5

AUTHORS INFORMATION

1 Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

2 Dept. of Anesthesia, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

3 Eye research Center, Imam Khomaeini Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

4 Dept. of Biostatistics, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

5 Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran

How to Cite: Yari M, Golfam P, Ariaietabar H, Sheikhi F, Yegane N, et al. Intravenous lidocaine on intraocular pressure in cataract surgery patients under sedation, J Kermanshah Univ Med Sci. 2012 ; 16(4):e78784.

ARTICLE INFORMATION

Journal of Kermanshah University of Medical Sciences: 16 (4); e78784
Published Online: November 29, 2012
Article Type: Research Article
Received: December 12, 2011
Accepted: April 24, 2012

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Abstract

Background: Decreasing intraocular pressure (IOP) and preventing the IOP rising during cataract surgery, is one of the most important factors in successful cataract surgery. This study was conducted to investigate the effects of intravenous lidocaine on IOP in cataract surgery under sedation.

Methods: The study was a double blind controlled trial which firstly, the patient’s IOP was measured. Then the patients were divided into two groups. The lidocaine (experimental) group had injected intravenous lidocaine and the control group had injected intravenous saline. Three minutes later after intervention, IOP was measured again. The data was analyzed using SPSS 15 software and Chi-square, independent t-test and Mann-Whitney tests.

Results: Mean age of participants was 56.6 (±9.7) years. The mean of IOP difference after and before intervention was -1.06(±3.96) mmHg (median: 0 and range: -15 to 2) and there was no significant statistical difference between two groups but it decreased more in those with higher pre-intervention intraocular pressure in lidocaine group.

Conclusion: A dose of 1.5 mg/kg of intravenous lidocaine may reduce intra ocular pressure of patients who have increased pre-operation IOP. In addition, lidocaine might be used when IOP increases suddenly during eye surgeries that are performed under sedation.

Keywords

intraocular pressure cataract lidocaine sedation

© 2012, Journal of Kermanshah University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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