Cardiac manifestation of normokalemic periodic paralysis in 21 years old male in Kermanshah

AUTHORS

Alireza Ray 1 , Shirin Rashidi Shahpasandi 1 , * , Parastou Shirvani 2

1 Dept. of Cardiology, School of Medicine, Kermanshah University of Medical Sciences , kermanshah, Iran

2 Emam Ali Hospital, Kermanshah University of Medical Sciences , kermanshah, Iran

How to Cite: Ray A, Shahpasandi S R, Shirvani P. Cardiac manifestation of normokalemic periodic paralysis in 21 years old male in Kermanshah, J Kermanshah Univ Med Sci. 2010 ; 13(4):e79590.

ARTICLE INFORMATION

Journal of Kermanshah University of Medical Sciences: 13 (4); e79590
Published Online: March 19, 2010
Article Type: Case Report
Received: June 24, 2009
Accepted: November 24, 2009

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Abstract

Background: Normokalemic periodic paralysis is an autosomal dominant disorder involving the abnormal function of skeletal muscle’s voltage-gated alpha-subunits. It is characterized by paralysis attack of varying severity with concomitant normal serum potassium concentration. Although normokalemic periodic paralysis is well established in the literature, but its cardiac manifestations are very rare.

Case Report: We present 21 years old age male, which referred to Imam Ali Hospital with severe palpitation, atypical angina and flaccid quadric paralysis.

Electrocardiographic manifestation was first-degree AV block, Bijeminated ventricular extrasystole and severe ST-T change in pericordial leads. Initial potassium level was 4 meq/l, CPK and aldolase level were normal. Echocardiography and exercise test were normal.

Conclusion: After four days administration of acetazolamide, his weakness was disappeared and ECG became normal. He discharged from hospital with normal neurological examination and effective treatment outcome.

Keywords

Normokalemic periodic paralysis cardiac manifestations ECG

© 2010, Journal of Kermanshah University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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