Comparing Fluconazole and Clotrimazole in treatment of candida albicans vaginitis

AUTHORS

NS Karimaan 1 , * , Z Shafaaii 1 , M Afraakhte 1 , N Valaaii 1 , M Ahmadi 1

AUTHORS INFORMATION

1 Iran

How to Cite: Karimaan N, Shafaaii Z, Afraakhte M, Valaaii N, Ahmadi M. Comparing Fluconazole and Clotrimazole in treatment of candida albicans vaginitis, J Kermanshah Univ Med Sci. 2002 ; 6(3):e81013.

ARTICLE INFORMATION

Journal of Kermanshah University of Medical Sciences: 6 (3); e81013
Published Online: December 19, 2002
Article Type: Research Article
Received: August 12, 2002
Accepted: December 11, 2002

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Abstract

Introduction and Objectives: This study was done to compare the effectiveness of  Fluconazole and Clotrimazole in treatment of candida albicans vaginitis in patients referring to health centers affiliated with Shahid Beheshti University, during the year 1379.

 Materials and Methods: 70 patients received either a single oral dose of 150 mg Fluconazole (35 patients)  or  7 days course of vaginal Clotrimazole. Clinical history, smear, and culture  were  obtained.

Results: Positive Clinical and laboratory response was seen in 77% and 74% and 91% and 77% of Fluconazole and Clotrimazole groups, respectively. There was no statistically significant differences between the 2 groups regarding clinical or laboratory responses to treatment.

Discussion and Conclusions: If confirmed by others, a single oral dose of 150 mg Fluconazole should replace the  7 days course of vaginal Clotrimazole.

Keywords

candida vulvovaginitis Fluconazole Clotrimazole

© 2002, Journal of Kermanshah University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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