The effect of endurance training on serum levels of pro-inflammatory cytokines, testosterone and cortisol in sedentary young men

AUTHORS

Abdolhossein Taheri Kalani 1 , * , Khosrow Ebrahim 1 , Mohammad Ali Azarbayjani 2

1 Dept. of Physical Education and Sport Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

2 Dept. of Physical Education and Sport Sciences, Central Tehran Branch, Islamic Azad University, Tehran, Iran

How to Cite: Taheri Kalani A, Ebrahim K, Azarbayjani M A. The effect of endurance training on serum levels of pro-inflammatory cytokines, testosterone and cortisol in sedentary young men, J Kermanshah Univ Med Sci. 2012 ; 16(4):e78783.

ARTICLE INFORMATION

Journal of Kermanshah University of Medical Sciences: 16 (4); e78783
Published Online: November 29, 2012
Article Type: Research Article
Received: August 24, 2011
Accepted: January 31, 2012

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Abstract

Background: Given widespread deleterious health effects of an augmented inflammatory state, identification of therapies that reduce inflammation is critical. The purpose of the present study was to investigate the effects of 10 weeks endurance training on pro-inflammatory cytokines and their relationships with cortisol and testosterone hormones in sedentary young men.

Methods: Twenty sedentary men (age, 20-30 yr), volunteers to participant in the study. They were randomly divided into two groups of endurance training (n=11) and control (n=9) group. Blood sample were collected before and after 5 and 10 weeks from intervention, and the concentrations of TNF-a, IL-1b, IL-6, cortisol and testosterone were measured. Endurance training included 30 min cycling on ergometer at 70% maximal heart rate, which was then increasingly changed to 50 min at 80% maximal heart rate in week 10.

Results: Endurance training increased VO2max, and decreased body fat percent (P<0.05),  but concentrations of TNF-a, IL-1b, IL-6, Cortisol and testosterone did not changed (P>0.05). In addition, Pearson’s correlation indicated no relationships between changes in pro-inflammatory cytokine concentrations and changes in hormones and body fat percent (P>0.05).

Conclusion: These results indicated that, 10 weeks endurance training has no significant effect on baseline pro-inflammatory cytokine concentrations and their relationships with cortisol and testosterone in sedentary young men.

Keywords

endurance training cytokine TNF- IL-1 IL-6

© 2012, Journal of Kermanshah University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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