Immune response to hepatitis B vaccine in health care workers of Kermanshah

AUTHORS

AR Janbakhsh 1 , * , H Hatami 1 , B Sayad 1 , P Aieni 1 , AH Hashemian 1

1 Iran

How to Cite: Janbakhsh A, Hatami H, Sayad B, Aieni P, Hashemian A. Immune response to hepatitis B vaccine in health care workers of Kermanshah, J Kermanshah Univ Med Sci. 2003 ; 7(1):e81203.

ARTICLE INFORMATION

Journal of Kermanshah University of Medical Sciences: 7 (1); e81203
Published Online: June 19, 2003
Article Type: Research Article
Received: March 15, 2003
Accepted: June 15, 2003

Crossmark

CHEKING

READ FULL TEXT
Abstract

Background & Objectives: hepatitis B is a major health problem in Iran. Although seroconversion in vaccinated persons is estimated to be more than 90%, immune response to hepatitis B vaccine have been reported to be varied in different studies. This study was done to assess the vaccine effects in health care workers (HCWs).

Materials and Methods: I this descriptive, cross sectional study, HBSAb titer in 138 HBCAb negative, vaccinated HCWs in 10 health care centers was assessed using ELISA method. Of 138 HCWs, 60.1% were females and 39.9 males.

Results: 69.9% developed protective immune response. Age was a significant factor in responsiveness. Sex, weight, and last vaccination time had no significant role.

Discussion: In our study, rate of immune response to hepatitis B was low. Thus, revaccination may be necessary for nonresponders. We suggest that cost-effectiveness of the Heberbiovac HB vaccine should be re-evaluated in high risk groups.

Keywords

hepatitis B immune response Heberbiovac HB HCWs HBV

© 2003, Journal of Kermanshah University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Fulltext

The full text of this article is available on PDF

COMMENTS

LEAVE A COMMENT HERE: